#Edge of obliteration free

To overcome these incongruences, a 3D dynamic responsive multilamellar scaffold has been developed for fixation-free inguinal hernia repair. Unfortunately, in conventional prosthetic herniorrhaphy no relationship exists between pathogenesis and treatment. As inguinal hernia is a degenerative disease, logically the treatment should aim at stopping degeneration and activating regeneration. Postoperative chronic pain caused by fixation and/or fibrotic incorporation of hernia meshes are the main concerns in inguinal herniorrhaphy. It seems to embody a more physiological and pathogenetically coherent concept of cure, thus improving treatment results of this widespread disease. Fixation free, dynamic responsive, permanent defect obliteration, histologically proven regenerative effects are the distinctive features of this 3D scaffold. The results achieved with the described laparoscopic technique seem to embody an innovative concept for inguinal hernia repair. No chronic pain and no recurrences were reported during follow up. In particular, early postoperative pain and discomfort significantly decreased. The technique proved effective in reducing intra and postoperative complications.

#Edge of obliteration free

The laparoscopic technique with the 3D hernia scaffold allowed for fixation free placement, permanent defect obliteration and dynamically induced regenerative effects. The procedures were carried out from January 2018 to January 2022 with a defined protocol and detailed procedural steps. Overall, 122 hernia defects were obliterated with 119 dynamic responsive scaffolds. The operated patients presented with bilateral and/or recurrent inguinal hernia. A laparoscopic approach with the 3D scaffold has been tested on 71 patients to demonstrate its effectiveness in reducing intra and postoperative complications. Following its inherent centrifugal expansion due to its dynamic responsivity, this hernia device is positioned fixation free within the defect and induces a probiotic biological response allowing for the re-establishment of the degenerated inguinal barrier. Based on a newly developed dynamic responsive 3D scaffold named ProFlor, a permanent hernia defect obliteration has been finalized. To overcome these concerns, recently a different concept of cure has emerged. These problems are considered the cause of frequent intra and postoperative complications. Furthermore, hernia defect patency represents another problem which seems not well acknowledged among surgeons.

As in the open approach, mesh fixation and poor-quality biologic response represent controversial questions and are a source of concerns. Laparoscopic TAPP/TEP approaches are well-established options for the cure of inguinal hernias.